All totals are U.S. box office only. Sci-fi and genre-related films are in BOLD.
1. The Game Plan………………….$16,609,377
Engagements:3,105 Cume: $43,158,823
2. The Heartbreak Kid……………..$14,022,105
Engagements:3,229 Cume: $14,022,105
3. The Kingdom…………………….$9,722,940
Engagements:2,802 Cume: $31,746,270
4. Resident Evil: Extinction………..$4,521,301
Engagements:2,848 Cume: $43,695,477
5. The Seeker: The Dark is Rising……$3,745,315
Engagements:3,141 Cume: $3,745,315
6. Good Luck Chuck…………………$3,657,516
Engagements:2,476 Cume: $29,255,442
7. 3:10 to Yuma……………………$3,215,469
Engagements:2,562 Cume: $48,728,753
8. Feel the Noise………………….$3,187,153
Engagements:1,015 Cume: $3,187,153
9. Mr. Woodcock……………………$2,331,445
Engagements:1,950 Cume: $22,613,590
10. The Brave One………………….$2,321,359
Engagements:2,358 Cume: $34,380,387
Source: Variety